Search results for "Cyclamen africanum"

showing 2 items of 2 documents

Two New Triterpene Saponins from Cyclamen africanumBoiss. & Reuter

2012

Two new oleanane-type triterpene saponins, afrocyclamins A and B (1 and 2, resp.), were isolated from a MeOH extract of the roots of Cyclamen africanum Boiss. & Reuter, together with three known triterpenoid saponins, lysikokianoside, deglucocyclamin I, and its dicrotalic acid derivative. The structures were elucidated, on the basis of 1D- and 2D-NMR experiments and mass spectrometry as (3β,20β)-13,28-epoxy-16-oxo-3-{O-β-D-xylopyranosyl-(12)-O-β-D-glucopyranosyl-(14)-O-[β-D-glucopyranosyl-(12)]-α-L-arabinopyranosyl}oxy}oleanan-29-al (1) and (3β,16α,20β)-16,28,29-trihydroxy-olean-12-en-3-yl O-4-O-(4-carboxy-3-hydroxy-3-methyl-1-oxobutyl)-β-D-xylopyranosyl-(12)-O-β-D-glucopyranosyl-(14)-O-[β-…

chemistry.chemical_classificationAcid derivativebiologyChemistryStereochemistryOrganic Chemistrybiology.organism_classificationMass spectrometryBiochemistryCatalysisInorganic ChemistryTerpeneCyclamen africanumTriterpenoidTriterpeneDrug DiscoveryPhysical and Theoretical ChemistryHelvetica Chimica Acta
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Isolement et caractérisation de saponosides extraits de deux plantes médicinales : Cyclamen africanum, Zygophyllum cornutum et évalution de leur acti…

2014

The appearance of several diseases, such as cancer, diabetes, high blood pressure and spread of infections mutagenic virus type can be linked to the quality and lifestyle that we lead today. Indeed, several studies on the factors triggering these so-called "morbid" long-or short-term illnesses are related to stress and quality of food consumed, whether of plant and animal origin. These diseases are becoming a common occurrence, they affect different races and all classes of society. According ethnobotanical research, naturally occurring substances, allowed civilizations to survive deadly diseases. For example, we thus find references to periods of malarial fever in China and one of the symp…

protéines réponse inflammatoire (PRI)[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyMass spectrometry1D and 2D NMRZygophyllum cornutumMédiateurs pro-inflammatoire (COX-2)Anti-inflammatoires (AINS)INOSPro-inflammatory mediatorsProtein inflammatory response (PRI)Activité anti inflammatoireAnti inflammatory activitySaponins triterpeneCyclamen africanumCOX-2Spectrométrie de masseRMN 1DRMN 2DSaponines triterpéniques[SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyAnti-inflammatory drugs (NSAIDs)TNF -αPGE2[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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